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Bacterial Protein Secretion Is Required for Priming of CD8(+) T Cells Specific for the Mycobacterium tuberculosis Antigen CFP10
Mycobacterium tuberculosis infection elicits antigen-specific CD8(+) T cells that are required to control disease. It is unknown how the major histocompatibility complex class I (MHC-I) pathway samples mycobacterial antigens. CFP10 and ESAT6 are important virulence factors secreted by M. tuberculosi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519428/ https://ncbi.nlm.nih.gov/pubmed/18591224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00307-08 |
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