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Vaccine-Elicited 10-Kilodalton Culture Filtrate Protein-Specific CD8(+) T Cells Are Sufficient To Mediate Protection against Mycobacterium tuberculosis Infection
The 10-kDa culture filtrate protein (CFP-10) and 6-kDa early secretory antigen of T cells (ESAT-6) are secreted in abundance by Mycobacterium tuberculosis and are frequently recognized by T cells from infected people. The genes encoding these proteins have been deleted from the genome of the vaccine...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2346695/ https://ncbi.nlm.nih.gov/pubmed/18332205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00024-08 |
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