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Vaccine-Elicited 10-Kilodalton Culture Filtrate Protein-Specific CD8(+) T Cells Are Sufficient To Mediate Protection against Mycobacterium tuberculosis Infection

The 10-kDa culture filtrate protein (CFP-10) and 6-kDa early secretory antigen of T cells (ESAT-6) are secreted in abundance by Mycobacterium tuberculosis and are frequently recognized by T cells from infected people. The genes encoding these proteins have been deleted from the genome of the vaccine...

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Detalhes bibliográficos
Main Authors: Wu, Ying, Woodworth, Joshua S., Shin, Daniel S., Morris, Sheldon, Behar, Samuel M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346695/
https://ncbi.nlm.nih.gov/pubmed/18332205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00024-08
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