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TBIO-21. ANALYSIS OF PAIRED BRAF(V600E) MUTANT GLIOMA PATIENT SAMPLES IDENTIFIES NOVEL RESISTANCE MECHANISMS TO TARGETED BRAF INHIBITION
BRAF(V600E) mutations occur in a variety of gliomas and BRAF(V600E) targeted therapies have provided new treatment options. Trials in melanoma and colorectal cancer, as well as early results in CNS tumors, indicate a high risk for the development of resistance. To date there is little data available...
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| Izdano u: | Neuro Oncol |
|---|---|
| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012902/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.709 |
| Oznake: |
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