PDTM-38. ANALYSIS OF PAIRED BRAF(V600E) MUTANT GLIOMA PATIENT SAMPLES IDENTIFIES NOVEL RESISTANCE MECHANISMS TO TARGETED BRAF INHIBITION

BRAFV600E mutations occur in a variety of gliomas including gangliogliomas, epithelioid glioblastomas, pleomorphic xanthroastrocytomas, and pilocytic astrocytomas. The development of BRAFV600E targeted therapies has provided a new treatment option for these patients. Clinical trials in melanoma and...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Levy, Jean Mulcahy, Sanford, Bridget, Morin, Andrew, Green, Adam, Flannery, Patrick, Jones, Kenneth, Banerjee, Anuradha, Solomon, David A, Nicolaides, Theo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692069/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.801
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