ATRT-24. CHROMATIN SEGMENTATION IN ATRT REVEALS AN IMPORTANT ROLE FOR RESIDUAL SWI/SNF MEMBERS

Although SMARCB1 mutations represent the only recurrent genetic aberration in atypical teratoid/rhabdoid tumors (ATRT), a comprehensive assessment of the epigenetic effect of SMARCB1 loss has not been attempted so far. To achieve this, we performed ChIP-sequencing for six histone marks (H3K4me1, H3K...

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Publicado en:Neuro Oncol
Autores principales: Johann, Pascal, Erkek, Serap, Finetti, Martina, Hasselblatt, Martin, Williamson, Daniel, Pfister, Stefan, Kool, Marcel
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012804/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.022
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