ATRT-05. USING DROSOPHILA TO EXPLORE THE FUNCTIONAL RELEVANCE OF GENES AFFECTED BY EPIGENETIC ALTERATIONS IN ATYPICAL TERATOID/RHABDOID TUMORS (AT/RT)

Atypical teratoid/rhabdoid tumors (AT/RT) are highly malignant brain tumors arising in young children. The majority of AT/RT is characterized by inactivation of one single gene, the chromatin remodeling complex member SMARCB1 (INI1/hSNF5). However, AT/RTs are epigenetically heterogeneous and can be...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Tegeder, Isabel, Thiel, Katharina, Berlandi, Johannes, Johann, Pascal, Erkek, Serap, Kool, Marcel, Jeibmann, Astrid, Hasselblatt, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012174/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.004
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