EPEN-34. HIGH-THROUGHPUT DRUG SCREENING OF PRIMARY CULTURES REVEALS IRREVERSIBLE ERBB2 INHIBITION AS NOVEL THERAPEUTIC VULNERABILITY OF EPENDYMOMAS

Ependymoma is the third most common brain tumor in children. Subsets of ependymomas, in particular RELA fusion-positive supratentorial ependymomas and posterior fossa type A ependymomas, are associated with frequent recurrence and dismal outcome. Neurosurgical resection and radiotherapy are the main...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Pauck, David, Sarikaya-Seiwert, Sevgi, Marquardt, Viktoria, Picard, Daniel, Bartl, Jasmin, Blümel, Lena, Maue, Mara, Dimitriadis, Christian, Kuhlen, Michaela, Fischer, Ute, Steiger, Hans-Jakob, Reifenberger, Guido, Borkhardt, Arndt, Beez, Thomas, Remke, Marc
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
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Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012724/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.234
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