EPEN-34. HIGH-THROUGHPUT DRUG SCREENING OF PRIMARY CULTURES REVEALS IRREVERSIBLE ERBB2 INHIBITION AS NOVEL THERAPEUTIC VULNERABILITY OF EPENDYMOMAS

Ependymoma is the third most common brain tumor in children. Subsets of ependymomas, in particular RELA fusion-positive supratentorial ependymomas and posterior fossa type A ependymomas, are associated with frequent recurrence and dismal outcome. Neurosurgical resection and radiotherapy are the main...

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Publicado no:Neuro Oncol
Main Authors: Pauck, David, Sarikaya-Seiwert, Sevgi, Marquardt, Viktoria, Picard, Daniel, Bartl, Jasmin, Blümel, Lena, Maue, Mara, Dimitriadis, Christian, Kuhlen, Michaela, Fischer, Ute, Steiger, Hans-Jakob, Reifenberger, Guido, Borkhardt, Arndt, Beez, Thomas, Remke, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012724/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.234
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