EPEN-34. HIGH-THROUGHPUT DRUG SCREENING OF PRIMARY CULTURES REVEALS IRREVERSIBLE ERBB2 INHIBITION AS NOVEL THERAPEUTIC VULNERABILITY OF EPENDYMOMAS

Ependymoma is the third most common brain tumor in children. Subsets of ependymomas, in particular RELA fusion-positive supratentorial ependymomas and posterior fossa type A ependymomas, are associated with frequent recurrence and dismal outcome. Neurosurgical resection and radiotherapy are the main...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Pauck, David, Sarikaya-Seiwert, Sevgi, Marquardt, Viktoria, Picard, Daniel, Bartl, Jasmin, Blümel, Lena, Maue, Mara, Dimitriadis, Christian, Kuhlen, Michaela, Fischer, Ute, Steiger, Hans-Jakob, Reifenberger, Guido, Borkhardt, Arndt, Beez, Thomas, Remke, Marc
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
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Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012724/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.234
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