LGG-37. ASSESSMENT OF EARLY STAGE AUTOPHAGY INHIBITION IN BRAF(V600E) BRAIN TUMOR CELL RESPONSE TO CHEMOTHERAPY

We have previously shown CNS tumors with the BRAF(V600E) mutation are autophagy dependent and late stage autophagy inhibition improves responses to targeted BRAF inhibitors (BRAFi) in sensitive and BRAFi resistant cells. Autophagy is a multi-stage process. Progress within the field has led to the de...

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發表在:Neuro Oncol
Main Authors: Zahedi, Shadi, Fitzwalter, Brent E, Gustafson, Daniel L, Morin, Andrew, Desmarais, Michele, Hoffman, Lindsey M, Levy, Jean M Mulcahy
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012672/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.378
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