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Using BRAF(V600E) as a marker of autophagy dependence in pediatric brain tumors
Autophagy inhibition is a potential therapeutic strategy in central nervous system (CNS) tumors. The BRAF(V600E) mutation is known to affect autophagy. Our studies indicate CNS tumor cells with BRAF(V600E) mutant cells (but not wild type) display high rates of induced autophagy, are sensitive to aut...
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| Publicado no: | Autophagy |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502777/ https://ncbi.nlm.nih.gov/pubmed/25484091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.36138 |
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