Autophagy Inhibition Improves Chemosensitivity in BRAF(V600E) Brain Tumors

Autophagy inhibition is a potential therapeutic strategy in cancer, but it is unknown which tumors will benefit. The BRAF(V600E) mutation has been identified as important in pediatric CNS tumors and is known to affect autophagy in other tumor types. We evaluated CNS tumor cells with BRAF(V600E) and...

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Bibliografiset tiedot
Päätekijät: Levy, Jean M. Mulcahy, Thompson, Joshua C., Griesinger, Andrea M., Amani, Vladimir, Donson, Andrew M., Birks, Diane K., Morgan, Michael J., Mirsky, David M., Handler, Michael H., Foreman, Nicholas K., Thorburn, Andrew
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090283/
https://ncbi.nlm.nih.gov/pubmed/24823863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-0049
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