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HGG-37. DETECTION OF IDH1 R132H MOSAICISM IN ANAPLASTIC ASTROCYTOMA PATIENTS
Anaplastic astrocytomas are aggressive glial cancers that present poor prognosis and high recurrence. Heterozygous mutations in the IDH1 (R132H) gene are common in adult anaplastic astrocytomas, but are uncommon in the pediatric population. In a majority of cases, the IDH1 R132H mutation is somatic,...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012671/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.309 |
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