HGG-37. DETECTION OF IDH1 R132H MOSAICISM IN ANAPLASTIC ASTROCYTOMA PATIENTS

Anaplastic astrocytomas are aggressive glial cancers that present poor prognosis and high recurrence. Heterozygous mutations in the IDH1 (R132H) gene are common in adult anaplastic astrocytomas, but are uncommon in the pediatric population. In a majority of cases, the IDH1 R132H mutation is somatic,...

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Publicado no:Neuro Oncol
Main Authors: Lee, Sulgi, Bornhorst, Miriam, Panditharatna, Eshini, Kambhamptai, Madhuri, Turner, Joyce, Packer, Roger J, Kilburn, Lindsay, Nazarian, Javad
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012671/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.309
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