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HGG-43. SUSTAINED RESPONSE OF THREE PEDIATRIC BRAF(V600E) MUTATED HIGH-GRADE GLIOMAS WITH BRAF AND MEK INHIBITOR THERAPY

BACKGROUND: Treating high-grade gliomas in pediatric patients involves multimodal therapy with significant long-term sequelae. Despite this approach, these tumors have a high rate of recurrence. Genetic testing has allowed for targeted therapies to be investigated in tumors with BRAF(V600E) mutation...

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Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Toll, Stephanie, Cotter, Jennifer, Judkins, Alexander, Tamrazi, Benita, Biegel, Jaclyn, Patel, Palak, Tran, Hung N, Cooper, Robert, Margol, Ashley S
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012624/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.314
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