Sustained response of three pediatric BRAF(V600E) mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy

Outcomes for children with high-grade gliomas (HGG) remain dismal despite aggressive treatment strategies. The use of targeted therapy for BRAF(V600E) mutated malignancies including HGG is being explored as a potentially well tolerated and effective therapeutic option. The results of adult melanoma...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Toll, Stephanie A., Tran, Hung N., Cotter, Jennifer, Judkins, Alexander R., Tamrazi, Benita, Biegel, Jaclyn A., Dhall, Girish, Robison, Nathan J., Waters, Kaaren, Patel, Palak, Cooper, Robert, Margol, Ashley S.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2019
Предметы:
Case Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355184/
https://ncbi.nlm.nih.gov/pubmed/30728904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26560
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