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MBRS-19. BIOCHEMICAL AND ONCOGENIC CHARACTERIZATION OF HOTSPOT KBTBD4 MUTATIONS IN MEDULLOBLASTOMA
Medulloblastoma (MB) is the most common malignant childhood brain tumor. Our recent analysis of the MB genomic landscape in a cohort of 500 patients discovered subgroup-specific hotspot mutations targeting KBTBD4, a poorly characterized member of the BTB-BACK-Kelch domain family of proteins. Based o...
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| Publicat a: | Neuro Oncol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012582/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.464 |
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