ATRT-12. TARGETING SIRT2 IN SMARCB1 DEFICIENT ATRT

Atypical Teratoid Rhabdoid Tumor (ATRT) is a highly aggressive and malignant pediatric brain tumor with poor outcomes. The central mechanism of ATRT tumorigenesis is SMARCB1 deficiency that leads to epigenetic dysregulation. To identify key epigenetic regulators that co-operate with SMARB1 deficienc...

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Publicado en:Neuro Oncol
Autores principales: Alimova, Irina, Venkataraman, Sujatha, Pierce, Angela M, Birks, Diane, Vibhakar, Rajeev, Foreman, Nicholas K, Yang, Min, Ling, Hinning
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012123/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.011
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