ATRT-12. TARGETING SIRT2 IN SMARCB1 DEFICIENT ATRT

Atypical Teratoid Rhabdoid Tumor (ATRT) is a highly aggressive and malignant pediatric brain tumor with poor outcomes. The central mechanism of ATRT tumorigenesis is SMARCB1 deficiency that leads to epigenetic dysregulation. To identify key epigenetic regulators that co-operate with SMARB1 deficienc...

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Pubblicato in:Neuro Oncol
Autori principali: Alimova, Irina, Venkataraman, Sujatha, Pierce, Angela M, Birks, Diane, Vibhakar, Rajeev, Foreman, Nicholas K, Yang, Min, Ling, Hinning
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012123/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.011
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