Wird geladen...
DIPG-60. PPM1D MUTATION MEDIATES TUMORIGENESIS AND IS A THERAPEUTIC TARGET IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)
While diffuse intrinsic pontine glioma (DIPG), the most common pediatric brainstem tumor, exhibits transient responsiveness to radiation (XRT), overall survival is <2% within two years of diagnosis. PPM1D is a serine/threonine protein phosphatase that is important in DNA damage response (DDR). Bu...
Gespeichert in:
| Veröffentlicht in: | Neuro Oncol |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012088/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.153 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|