The stress regulator FKBP51: a novel and promising druggable target for the treatment of persistent pain states across sexes

It is well established that FKBP51 regulates the stress system by modulating the sensitivity of the glucocorticoid receptor to stress hormones. Recently, we have demonstrated that FKBP51 also drives long-term inflammatory pain states in male mice by modulating glucocorticoid signalling at spinal cor...

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Publicado en:Pain
Autores principales: Maiarù, Maria, Morgan, Oakley B., Mao, Tianqi, Breitsamer, Michaela, Bamber, Harry, Pöhlmann, Max, Schmidt, Mathias V., Winter, Gerhard, Hausch, Felix, Géranton, Sandrine M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012049/
https://ncbi.nlm.nih.gov/pubmed/29533388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001204
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