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The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling
Polymorphisms in FKBP51 are associated with stress-related psychiatric disorders and influence the severity of pain symptoms experienced after trauma. Here, we report that FKBP51 (FK506 binding protein 51) is crucial for the full development and maintenance of long-term pain states and that this is...
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| Publicado no: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4880036/ https://ncbi.nlm.nih.gov/pubmed/26865567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aab3376 |
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