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DIPG-67. HYPOXIA-INDUCIBLE FACTORS REGULATE DIFFUSE INTRINSIC PONTINE GLIOMA GROWTH IN NORMOXIC CULTURE

Diffuse intrinsic pontine glioma (DIPG) are incurable tumors and the leading cause of pediatric brain tumor deaths. They exhibit low blood perfusion and regions of necrosis, indicative of a low-oxygen environment that supports activation of hypoxia-inducible factors (HIF) that are associated with in...

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Publicat a:Neuro Oncol
Autors principals: Waker, Christopher, Keoni, Chanel, Schurko, Brianna, Brown, Thomas, Lober, Robert
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011885/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.160
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