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DIPG-67. HYPOXIA-INDUCIBLE FACTORS REGULATE DIFFUSE INTRINSIC PONTINE GLIOMA GROWTH IN NORMOXIC CULTURE

Diffuse intrinsic pontine glioma (DIPG) are incurable tumors and the leading cause of pediatric brain tumor deaths. They exhibit low blood perfusion and regions of necrosis, indicative of a low-oxygen environment that supports activation of hypoxia-inducible factors (HIF) that are associated with in...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Waker, Christopher, Keoni, Chanel, Schurko, Brianna, Brown, Thomas, Lober, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011885/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.160
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