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Mechanism of indinavir-induced hyperbilirubinemia

Indinavir is a viral protease inhibitor used for the treatment of HIV infection. Unconjugated hyperbilirubinemia develops in up to 25% of patients receiving indinavir, prompting drug discontinuation and further clinical evaluation in some instances. We postulated that this side-effect is due to indi...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Zucker, Stephen D., Qin, Xiaofa, Rouster, Susan D., Yu, Fei, Green, Richard M., Keshavan, Pavitra, Feinberg, Judith, Sherman, Kenneth E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2001
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60112/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11606755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.231140698
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