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Mechanism of indinavir-induced hyperbilirubinemia

Indinavir is a viral protease inhibitor used for the treatment of HIV infection. Unconjugated hyperbilirubinemia develops in up to 25% of patients receiving indinavir, prompting drug discontinuation and further clinical evaluation in some instances. We postulated that this side-effect is due to indi...

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Detalhes bibliográficos
Main Authors: Zucker, Stephen D., Qin, Xiaofa, Rouster, Susan D., Yu, Fei, Green, Richard M., Keshavan, Pavitra, Feinberg, Judith, Sherman, Kenneth E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60112/
https://ncbi.nlm.nih.gov/pubmed/11606755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231140698
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