IL‐7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum‐infected mice

In schistosomiasis japonica and mansoni, parasite eggs trapped in host liver elicit severe liver granulomatous inflammation that subsequently leads to periportal fibrosis, portal hypertension, haemorrhage or even death. Macrophages are critical for granuloma formation and the development of liver fi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cell Mol Med
Päätekijät: Zhu, Jifeng, Zhang, Weiwei, Zhang, Lina, Xu, Lei, Chen, Xiaojun, Zhou, Sha, Xu, Zhipeng, Xiao, Ming, Bai, Hui, Liu, Feng, Su, Chuan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010884/
https://ncbi.nlm.nih.gov/pubmed/29566311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13610
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