IL‐7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum‐infected mice

In schistosomiasis japonica and mansoni, parasite eggs trapped in host liver elicit severe liver granulomatous inflammation that subsequently leads to periportal fibrosis, portal hypertension, haemorrhage or even death. Macrophages are critical for granuloma formation and the development of liver fi...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhu, Jifeng, Zhang, Weiwei, Zhang, Lina, Xu, Lei, Chen, Xiaojun, Zhou, Sha, Xu, Zhipeng, Xiao, Ming, Bai, Hui, Liu, Feng, Su, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010884/
https://ncbi.nlm.nih.gov/pubmed/29566311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13610
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