Parasitic antigens alter macrophage polarization during Schistosoma japonicum infection in mice

BACKGROUND: Schistosome eggs are trapped in host liver and elicit severe hepatic granulomatous inflammation, which can lead to periportal fibrosis, portal hypertension, hemorrhage, or even death in the host. It was reported that the macrophage plays an important role in host immune responses to schi...

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Hauptverfasser: Zhu, Jifeng, Xu, Zhipeng, Chen, Xiaojun, Zhou, Sha, Zhang, Weiwei, Chi, Ying, Li, Wei, Song, Xian, Liu, Feng, Su, Chuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975460/
https://ncbi.nlm.nih.gov/pubmed/24666892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-7-122
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