Lipin‐1 determines lung cancer cell survival and chemotherapy sensitivity by regulation of endoplasmic reticulum homeostasis and autophagy

Cancer cells undergo comprehensive metabolic reprogramming to meet the increased requirements of energy and building blocks for proliferation. Lipin‐1, a phosphatidic acid phosphatase converting phosphatidic acid (PA) to diacylglycerol (DAG), is upregulated in lung adenocarcinoma (LUAD) cell lines a...

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Bibliografske podrobnosti
izdano v:Cancer Med
Main Authors: Fan, Xueyu, Weng, Yuanyuan, Bai, Yongfeng, Wang, Zongpan, Wang, Siwei, Zhu, Jin, Zhang, Feng
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Cancer Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010863/
https://ncbi.nlm.nih.gov/pubmed/29659171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1483
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