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Elevated CRB3 expression suppresses breast cancer stemness by inhibiting β‐catenin signalling to restore tamoxifen sensitivity

Tamoxifen is a first‐line drug for hormone therapy (HT) in oestrogen receptor‐positive breast cancer patients. However, 20% to 30% of those patients are resistant to tamoxifen treatment. Cancer stem cells (CSCs) have been implicated as one of the mechanisms responsible for tamoxifen resistance. Our...

詳細記述

保存先:
書誌詳細
出版年:J Cell Mol Med
主要な著者: Li, Pingping, Feng, Chen, Chen, He, Jiang, Yina, Cao, Fang, Liu, Jie, Liu, Peijun
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010813/
https://ncbi.nlm.nih.gov/pubmed/29602199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13619
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