Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling

Objective: Cancer stem cells (CSCs) are responsible for the drug resistance of breast cancers. Vitamin D deficiency promotes tumor resistance. The present study examined the effect of vitamin D and vitamin D receptor (VDR) expression on the tamoxifen resistance of CSCs. Methods: MCF-7 cells were tre...

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Bibliographische Detailangaben
Veröffentlicht in:Biosci Rep
Hauptverfasser: Zheng, Wei, Duan, Bofeng, Zhang, Qian, Ouyang, Linna, Peng, Wei, Qian, Fuyong, Wang, Yibin, Huang, Shiting
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2018
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435469/
https://ncbi.nlm.nih.gov/pubmed/30314996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180595
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