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The TLR4‐IRE1α pathway activation contributes to palmitate‐elicited lipotoxicity in hepatocytes
Lipotoxicity induced by saturated fatty acids (SFAs) plays a pathological role in the development of non‐alcoholic fatty liver disease (NAFLD); however, the exact mechanism(s) remain to be clearly elucidated. Toll‐like receptor (TLR) 4 plays a fundamental role in activating the innate immune system....
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| Publicado no: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6010797/ https://ncbi.nlm.nih.gov/pubmed/29673059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13636 |
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