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Glucocorticoids modulate multidrug resistance transporters in the first trimester human placenta
The placental multidrug transporters, P‐glycoprotein (P‐gp, encoded by ABCB1) and breast cancer resistance protein (BCRP,ABCG2) protect the foetus from exposure to maternally derived glucocorticoids, toxins and xenobiotics. During pregnancy, maternal glucocorticoid levels can be elevated by stress o...
Enregistré dans:
| Publié dans: | J Cell Mol Med |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6010777/ https://ncbi.nlm.nih.gov/pubmed/29691980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13646 |
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