Endoplasmic reticulum stress induces spatial memory deficits by activating GSK‐3

Endoplasmic reticulum (ER) stress is involved in Alzheimer's disease (AD), but the mechanism is not fully understood. Here, we injected tunicamycin (TM), a recognized ER stress inducer, into the brain ventricle of Sprague‐Dawley (SD) rats to induce the unfolded protein response (UPR), demonstra...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Lin, Li, Cao, Jie, Yang, Shu‐Sheng, Fu, Zheng‐Qi, Zeng, Peng, Chu, Jiang, Ning, Lin‐Na, Zhang, Teng, Shi, Yan, Tian, Qing, Zhou, Xin‐Wen, Wang, Jian‐Zhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010738/
https://ncbi.nlm.nih.gov/pubmed/29675957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13626
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