Endoplasmic reticulum stress induces spatial memory deficits by activating GSK‐3

Endoplasmic reticulum (ER) stress is involved in Alzheimer's disease (AD), but the mechanism is not fully understood. Here, we injected tunicamycin (TM), a recognized ER stress inducer, into the brain ventricle of Sprague‐Dawley (SD) rats to induce the unfolded protein response (UPR), demonstra...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Lin, Li, Cao, Jie, Yang, Shu‐Sheng, Fu, Zheng‐Qi, Zeng, Peng, Chu, Jiang, Ning, Lin‐Na, Zhang, Teng, Shi, Yan, Tian, Qing, Zhou, Xin‐Wen, Wang, Jian‐Zhi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010738/
https://ncbi.nlm.nih.gov/pubmed/29675957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13626
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