Transforming Growth Factor-β and Interleukin-10 Synergistically Regulate Humoral Immunity via Modulating Metabolic Signals

Inhibitory cytokines, such as transforming growth factor-β (TGF-β) and interleukin-10 (IL-10), are humoral factors involved in the suppressive function of regulatory T cells and play critical roles in maintaining immune homeostasis. However, TGF-β and IL-10 also have pleiotropic effects and induce h...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Komai, Toshihiko, Inoue, Mariko, Okamura, Tomohisa, Morita, Kaoru, Iwasaki, Yukiko, Sumitomo, Shuji, Shoda, Hirofumi, Yamamoto, Kazuhiko, Fujio, Keishi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010538/
https://ncbi.nlm.nih.gov/pubmed/29963056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01364
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