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Detection of DT-diaphorase Enzyme with a ParaCEST MRI Contrast Agent

A responsive magnetic resonance (MRI) contrast agent has been developed that can detect the enzyme activity of DT-diaphorase. The agent produced different chemical exchange saturation transfer (CEST) MRI signals before and after incubation with the enzyme, NADH, and GSH at different pH values wherea...

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Détails bibliographiques
Publié dans:Chemistry
Auteurs principaux: Daryaei, Iman, Jones, Kyle M., Pagel, Mark D.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010184/
https://ncbi.nlm.nih.gov/pubmed/28370655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201700721
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