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CoCEST: Cobalt(II) Amide-Appended ParaCEST MRI Contrast Agents

The first examples of air-stable Co(II) paraCEST MRI contrast agents are reported. Amide NH protons on the complexes give rise to CEST peaks that are shifted up to 112 ppm from the bulk water resonance. One complex has multiple CEST peaks that may be useful for ratiometric mapping of pH.

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Dades bibliogràfiques
Autors principals: Dorazio, Sarina J., Olatunde, Abiola O., Spernyak, Joseph A., Morrow, Janet R.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857136/
https://ncbi.nlm.nih.gov/pubmed/24045271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc45000g
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