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Detection of sulfatase enzyme activity with a catalyCEST MRI contrast agent
A Chemical Exchange Saturation Transfer (CEST) MRI contrast agent has been developed that detects sulfatase enzyme activity. The agent produces a CEST signal at 5.0 ppm before enzyme activity, and a second CEST signal appears at 9.0 ppm after the enzyme cleaves a sulfate group from the agent. The co...
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| Publicado no: | Chemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4877021/ https://ncbi.nlm.nih.gov/pubmed/26956002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201600685 |
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