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A catalyCEST MRI contrast agent that detects the enzyme-catalyzed creation of a covalent bond

CatalyCEST MRI can detect enzyme activity by employing contrast agents that are detected through Chemical Exchange Saturation Transfer (CEST). A CEST agent, Tm-DO3A-cadaverine, has been designed to detect the catalytic activity of transglutaminase (TGase), which creates a covalent bond between the a...

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Detalhes bibliográficos
Main Authors: Hingorani, Dina V., Randtke, Edward A., Pagel, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667154/
https://ncbi.nlm.nih.gov/pubmed/23601132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja400254e
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