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A catalyCEST MRI contrast agent that can simultaneously detect two enzyme activities

The simultaneous detection of multiple enzyme activities can improve the specificity of disease diagnoses. We have synthesized and characterized a diamagnetic CEST MRI contrast agent that can simultaneously detect two enzyme activities. Sulfatase and esterase enzymes cleaved the ligands of the CEST...

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Détails bibliographiques
Publié dans:Chembiochem
Auteurs principaux: Fernández-Cuervo, Gabriela, Sinharay, Sanhita, Pagel, Mark D.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814164/
https://ncbi.nlm.nih.gov/pubmed/26693680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500586
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