Biochemical characterisation of a Kunitz-type inhibitor from Tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity

A trypsin inhibitor isolated from tamarind seed (TTI) has satietogenic effects in animals, increasing the cholecystokinin (CCK) in eutrophy and reducing leptin in obesity. We purified TTI (pTTI), characterised, and observed its effect upon CCK and leptin in obese Wistar rats. By HPLC, and after ampl...

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發表在:J Enzyme Inhib Med Chem
Main Authors: de Medeiros, Amanda Fernandes, Costa, Izael de Sousa, de Carvalho, Fabiana Maria Coimbra, Kiyota, Sumika, de Souza, Beatriz Blenda Pinheiro, Sifuentes, Daniel Nogoceke, Serquiz, Raphael Paschoal, Maciel, Bruna Leal Lima, Uchôa, Adriana Ferreira, dos Santos, Elizeu Antunes, Morais, Ana Heloneida de Araújo
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2018
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010142/
https://ncbi.nlm.nih.gov/pubmed/29322840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1419220
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