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Advances in the discovery of cathepsin K inhibitors on bone resorption
Cathepsin K (Cat K), highly expressed in osteoclasts, is a cysteine protease member of the cathepsin lysosomal protease family and has been of increasing interest as a target of medicinal chemistry efforts for its role in bone matrix degradation. Inhibition of the Cat K enzyme reduces bone resorptio...
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| Veröffentlicht in: | J Enzyme Inhib Med Chem |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6010086/ https://ncbi.nlm.nih.gov/pubmed/29723068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1465417 |
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