Advances in the discovery of cathepsin K inhibitors on bone resorption

Cathepsin K (Cat K), highly expressed in osteoclasts, is a cysteine protease member of the cathepsin lysosomal protease family and has been of increasing interest as a target of medicinal chemistry efforts for its role in bone matrix degradation. Inhibition of the Cat K enzyme reduces bone resorptio...

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Bibliografiske detaljer
Udgivet i:J Enzyme Inhib Med Chem
Main Authors: Lu, Jun, Wang, Maolin, Wang, Ziyue, Fu, Zhongqi, Lu, Aiping, Zhang, Ge
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010086/
https://ncbi.nlm.nih.gov/pubmed/29723068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1465417
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