Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid

Pharmacological interventions targeting mitochondria present several barriers for a complete efficacy. Therefore, a new mitochondriotropic antioxidant (AntiOxBEN(3)) based on the dietary antioxidant gallic acid was developed. AntiOxBEN(3) accumulated several thousand-fold inside isolated rat liver m...

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Dettagli Bibliografici
Pubblicato in:J Enzyme Inhib Med Chem
Autori principali: Teixeira, José, Oliveira, Catarina, Cagide, Fernando, Amorim, Ricardo, Garrido, Jorge, Borges, Fernanda, Oliveira, Paulo J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010063/
https://ncbi.nlm.nih.gov/pubmed/29513043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1442831
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