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Involvement of Mitochondrial Permeability Transition Pore (mPTP) in Cardiac Arrhythmias: Evidence from Cyclophilin D Knockout Mice

In the present study, we have used a genetic mouse model that lacks cyclophilin D (CypD KO) to assess the cardioprotective effect of mitochondrial permeability transition pore (mPTP) inhibition on Ca(2+) waves and Ca(2+) alternans at the single cell level, and cardiac arrhythmias in whole-heart prep...

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Vydáno v:Cell Calcium
Hlavní autoři: Gordan, Richard, Fefelova, Nadezhda, Gwathmey, Judith K, Xie, Lai-Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127715/
https://ncbi.nlm.nih.gov/pubmed/27616659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2016.09.001
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