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Iron Overload, Oxidative Stress and Calcium Mishandling in Cardiomyocytes: Role of the Mitochondrial Permeability Transition Pore

Iron (Fe) plays an essential role in many physiological processes. Hereditary hemochromatosis or frequent blood transfusions often cause iron overload (IO), which can lead to cardiomyopathy and arrhythmias; however, the underlying mechanism is not well defined. In the present study, we assess the hy...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Gordan, Richard, Fefelova, Nadezhda, Gwathmey, Judith K., Xie, Lai-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465659/
https://ncbi.nlm.nih.gov/pubmed/32824344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9080758
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