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Identification of cisplatin-binding sites on the large cytoplasmic loop of the Na(+)/K(+)-ATPase
Cisplatin is the most widely used chemotherapeutic drug for the treatment of various types of cancer; however, its administration brings also numerous side effects. It was demonstrated that cisplatin can inhibit the Na(+)/K(+)-ATPase (NKA), which can explain a large part of the adverse effects. In t...
Enregistré dans:
| Publié dans: | J Enzyme Inhib Med Chem |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6009960/ https://ncbi.nlm.nih.gov/pubmed/29577756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1445735 |
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