Tertiary amine derivatives of chlorochalcone as acetylcholinesterase (AChE) and buthylcholinesterase (BuChE) inhibitors: the influence of chlorine, alkyl amine side chain and α,β-unsaturated ketone group

A new series of tertiary amine derivatives of chlorochalcone (4a∼4l) were designed, synthesized and evaluated for the effect on acetylcholinesterase (AChE) and buthylcholinesterase (BuChE). The results indicated that all compounds revealed moderate or potent inhibitory activity against AChE, and som...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Enzyme Inhib Med Chem
Egile Nagusiak: Gao, Xiao-hui, Zhou, Chao, Liu, Hao-ran, Liu, Lin-bo, Tang, Jing-jing, Xia, Xin-hua
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009910/
https://ncbi.nlm.nih.gov/pubmed/27801600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1243534
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