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Structural Isomerism and Enhanced Lipophilicity of Pyrithione Ligands of Organoruthenium(II) Complexes Increase Inhibition on AChE and BuChE

The increasing number of Alzheimer’s disease (AD) cases requires the development of new improved drug candidates, possessing the ability of more efficient treatment as well as less unwanted side effects. Cholinesterase enzymes are highly associated with the development of AD and thus represent impor...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Kladnik, Jerneja, Ristovski, Samuel, Kljun, Jakob, Defant, Andrea, Mancini, Ines, Sepčić, Kristina, Turel, Iztok
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460603/
https://ncbi.nlm.nih.gov/pubmed/32781544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165628
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