Tricyclic coumarin sulphonate derivatives with alkaline phosphatase inhibitory effects: in vitro and docking studies

Tissue-nonspecific alkaline phosphatase (TNAP) is an important isozyme of alkaline phosphatases, which plays different pivotal roles within the human body. Most importantly, it is responsible for maintaining the balanced ratio of phosphate and inorganic pyrophosphate, thus regulates the extracellula...

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Bibliographic Details
Published in:J Enzyme Inhib Med Chem
Main Authors: Iqbal, Jamshed, El-Gamal, Mohammed I., Ejaz, Syeda Abida, Lecka, Joanna, Sévigny, Jean, Oh, Chang-Hyun
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009858/
https://ncbi.nlm.nih.gov/pubmed/29390901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1428193
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