Coumarin derivatives bearing benzoheterocycle moiety: synthesis, cholinesterase inhibitory, and docking simulation study

OBJECTIVE(S): To investigate the efficiency of a novel series of coumarin derivatives bearing benzoheterocycle moiety as novel cholinesterase inhibitors. MATERIALS AND METHODS: Different 7-hydroxycoumarin derivatives were synthesized via Pechmann or Knoevenagel condensation and conjugated to differe...

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Detalhes bibliográficos
Publicado no:Iran J Basic Med Sci
Main Authors: Hirbod, Kimia, Jalili-baleh, Leili, Nadri, Hamid, ebrahimi, Seyed esmaeil Sadat, Moradi, Alireza, Pakseresht, Bahar, Foroumadi, Alireza, Shafiee, Abbas, Khoobi, Mehdi
Formato: Artigo
Idioma:Inglês
Publicado em: Mashhad University of Medical Sciences 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569448/
https://ncbi.nlm.nih.gov/pubmed/28868119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2017.8830
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